Crusade begins after a savage attack on Earth by the Drakh, once the allies of the evil Shadows before thier departure beyond the Rim. Earth's humans have succeeded in defeating the Drakh force with the help of the Interstellar Alliance lead by President John Sheridan, but not its final revenge: a biogenetic plague that will eliminate all human life on Earth within five years, unless a cure can be found. Earth's scientists realize that they have no hope of developing a cure within that time period. So the White Star Fleet - led by the advanced prototype warship Excalibur staffed by a team of soldiers and scientists is sent to comb the ruins of alien civilizations far more advanced than humans to find the cure that will help save Earth.
Captain Matthew Gideon is summoned to Mars, where he is to take command of the Excalibur to begin the mission to find a cure for the Drakh plague somewhere in the depths of space. Captain Gideon was handpicked to command the Excalibur by ISA President John Sheridan. The first challenge Gideon faces is assembling his crew; with some reluctance about bringing Dureena Nafeel onto the crew as she was a member of the Thieves Guild, however Gideon was able to get her onboard, she then informed him of Galen the techno-mage. Galen meets with Gideon on a planet and after questioning Gideon he agrees to join the crew. With his crew assembled Gideon begins the search for the cure to the Drakh plague.
Note: Crusade is a spin-off from the Babylon 5 TV series. The TV movie Babylon 5: A Call to Arms which aired on TNT is the set up for the Crusade TV series.
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